產(chǎn)品編號：Y3246
英文名稱：8-Methoxypsoralen
CAS號 298-81-7  
分析標準品,≥98%
分子式 C12H8O4 分子量216.19

基本信息:

密度 1.368
熔點 143-148°C
溶解性 Soluble in acetone, ethanol (slight), acetic acid, and chloroform (50 mg/ml). Insoluble in water.
描述 
別名 花椒毒素;甲氧基補骨脂素;甲氧沙林;8-MOP;9-甲氧基呋喃并[3,2-g][1]苯并吡喃-7-酮;花椒毒內(nèi)酯;8-MOP;Ammoidin;Methoxsalen;Xanthotoxin;9-Methoxyfuro[3,2-g][1]benzopyran-7-one
生化機理 8-Methoxypsoralen is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). As a member of the foranocoumarins, 8-Methoxypsoralen has shown more potency than 5-MOP, 5-OH-P , DH-8-MOP and psoralen in the inhibiton of CYP2B1 (cytochrome P-450 2B1). 8-Methoxypsoralen has been shown to completely inhibit the metabolism of nicotine in vitro. The compound has been observed to inhibit the metabolism of theophylline,caffeine,hexobarbital and phenytoin.
應用 A potent suicide inhibitor of cytochrome P-450.